For patients navigating Chronic Inflammatory Response Syndrome (CIRS), persistent fatigue is often one of the most debilitating symptoms — yet also one of the most misunderstood. This is not ordinary tiredness, nor does it respond reliably to rest, dietary changes, or typical energy-boosting strategies.

Atrophy and Advanced Patterns in CIRS

Not all brain changes in CIRS follow the typical patterns of swelling or atrophy

What do you need to know about Actinobacteria in the context of CIRS?

What’s New on the Research Front with CIRS?

Understanding the Cognitive Impact of CIRS – Why Brain Fog Isn’t "Just in Your Head"

The Hidden Environmental Triggers of CIRS – Why Your Home Might Be Making You Sick